Current position 

Director of the Multi-Omics Laboratory, Institute of Life Sciences, Guangxi Medical University 

 

Subjects taught 

Bioinformatics, Applied Bioinformatics, Medical Bioinformatics 

 

Research interests 

Biomedical engineering and big data information analysis 
 

Research and publications 

Papers published in the last five years as first/corresponding author: 

(1) Wenqiang Shi#, Mang Shi#, Teng-Cheng Que#, Xiao-Ming Cui#, Run-Ze Ye#, Luo-Yuan Xia, Xin Hou, Jia-Jing Zheng, Na Jia, Xing Xie, Wei-Chen Wu, Mei-Hong He, Hui-Feng Wang, Yong-Jie Wei, Ai-Qiong Wu, Sheng-Feng Zhang, Yu-Sheng Pan, Pan-Yu Chen, Qian Wang, Shou-Sheng Li, Yan-Li Zhong, Ying-Jiao Li, Luo-Hao Tang, Lin Zhao, Jia-Fu Jiang*, Yan-Ling Hu* and Wu-Chun Cao*. Trafficked Malayan pangolins contain viral pathogens of humans. Nature microbiology. Accepted, 2022.（IF=30.964） 

(2) Que T#, Li J#, He Y#, Chen P, Lin W, He M, Yu L, Wu A, Tan L, Li Y, Hu Y*, Tong Y*. Human parainfluenza 3 and respiratory syncytial viruses detected in pangolins. Emerg Microbes Infect. 2022 Dec;11(1):1657-1663.（IF=19.568） 

(3) Ye R#, Que T#, Xia L#, Cui X, Zhang Y, Jiang J, Wang Q, Wang Q, He M, Shi W, Du L, Wei Y, Fan H, Wu Y, Liu J, Zheng J, Pan Y, Chen P, Li S, Zhong Y, Li Y, Tang L, Hu Y*, Cao W*, Jia N*. Natural infections with human respiratory syncytial viruses in non-primate animals, pangolins. Current biology, 2022, 2. (IF:10.834) 

(4) Shengfeng Zhang, Xing Xie, Lei Yu, Nili Jiang, Xihua Wei, Yanling Hu*. Investigating Causal Relations between Genetic Related Intermediate Endophenotype and Risk of Chronic Prostatitis: Mendelian Randomisation Study. Oxidative Medicine and Cellular Longevity. Accepted, 2022. （IF=7.31） 

(5) Fengjuan Tian#, Jing Li#, Wenli Liu, Yujie Liu, Yunjia Hu, Qihang Tu, Yang Li, Yu Bai, Mang Shi*, Tengcheng Que*, Yanling Hu*, Yigang Tong*. Virome in healthy pangolins revealed compatibility with multiple potentially zoonotic viruses. Zoological Research. 2022, Accepted.(IF= 6.975) 

(6) Que T#, Pang X#, Huang H#, Chen P, Wei Y, Hua Y, Li S, Wu A, He M, Hu Y *. Comparative gut microbiome in Trachypithecus leucocephalus and other primates in Guangxi, China basing on metagenome sequencing. Frontiers Cellular and Infection Microbiology, 2022,3 (Accepted, IF: 5.29) 

(7) Wei Y#, Wei H#, Wei Y#, Tan A, Chen X, Liao X, Xie B, Wei X, Li L, Liu Z, Dai S, Khan A, Pang X, Hassan N, Xiong K, Zhang K, Leng J, Lv J*, Hu Y*. Screening and Identification of Human Endogenous Retrovirus-K mRNAs for Breast Cancer Through Integrative Analysis of Multiple Datasets. Frontiers in Oncology. 2022, 2.16. (IF:6.244) 

(8) Pang X#, Li P#, Zhang L#, Que L#, Dong M#, Xie B#, Wang Q, Wei Y, Xie X, Li L, Yin C, Wei L, Huang K, Hua Y, Zhou Q, Li Y, Yu L, Li W, Mo Z, Zhang M, Leng J*, Hu Y*. Emerging Severe Acute Respiratory Syndrome Coronavirus 2 Mutation Hotspots Associated With Clinical Outcomes and Transmission. Front Microbiol. 2021, 12:753823. (IF:5.640) 

(9) Tengcheng Que#; Huifeng Wang#; Weifei Yang#; Jianbao Wu#; Chenyang Hou#;Surui Pei; Qunying Wu; LiuMing Li; Shilu Wei; Xing Xie; Hongli Huang; Panyu Chen; Yiming Huang; Yiming Huang; Meihong He; Dengpan Nong; Xiao Wei; Junyi Wu;Ru Nong; Ning Huang; Qingniao Zhou; Yaowang Lin; Tingxi Lu; Yongjie Wei; Shousheng Li; Jianglong Yao; Yanli Zhong; Huayong Qin; Luohao Tan; Yingjiao Li;Weidong Li; Tao Liu; Sanyang Liu; Yongyi Yu; Hong Qiu; Yonghua Jiang; Youcheng Li; Zhijin Liu; ChengMing Huang*; Yanling hu*; The reference genome and transcriptome of the limestone langur, Trachypithecus leucocephalus, reveal expansion of genes related to alkali tolerance, BMC biology, 2021, 0(0): 0-15. (IF: 7.431） 

(10) Hou C#, Hou Q#, Xie X, Wang H, Chen Y, Lu T, Wu Q, Liang Y, Hu Y*, Mao Y*. Serum iron status and the risk of breast cancer in the European population: a two-sample Mendelian randomisation study. Genes Nutr. 2021 Jul 6;16(1):9. (IF: 5.523 ） 

(11) Qunying Wu#; Xing Xie#; Yiming Huang#; Shanshan Meng; Youcheng Li; Huifeng Wang*; Yanling Hu*; N6-methyladenosine RNA methylation regulators contribute to the progression of prostate cancer, Journal of Cancer, 2021, 12(3 ): 682-692. (IF: 4.207） 

(12) Tommy Tsan-Yuk Lam#; Na Jia#; Ya-Wei Zhang#; Marcus Ho-Hin Shum#; Jia-Fu Jiang#; Hua-Chen Zhu; Yi-Gang Tong#; Yong-Xia Shi; Xue-Bing Ni; Yun-Shi Liao; Wen-Juan Li; Bao-Gui Jiang; Wei Wei; Ting-Ting Yuan; Kui Zheng; Xiao-Ming Cui; Jie Li; Guang-Qian Pei; Xin Qiang; William Yiu-Man Cheung; Lian-Feng Li; Fang-Fang Sun; Si-Qin; Ji-Cheng Huang; Gabriel M. Leung; Edward C. Holmes; Yan-Ling Hu*; Yi Guan*; Wu-Chun Cao*; Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins, Nature, 2020, 583(7815): 282-285. (IF: 49.962） 

(13) Wei W#, Li J, Wang YW, Jiang BG, Liu HB, Wei R, Jiang RR, Cui XM, Li LF, Yuan TT, Wang Q, Zhao L, Xia LY, Jiang JF, Qiu YF, Jia N, Cao WC*, Hu YL*. Anaplasma platys-Like Infection in Goats, Beijing, China. Vector Borne Zoonotic Dis. 202, 20(10):755-762. ( IF: 2.041) 

(14)  Li LF#, Wei R#, Liu HB, Jiang BG, Cui XM, Wei W, Yuan TT, Wang Q, Zhao L, Xia LY, Li J, Jiang JF, Jia N*, Hu YL*. Characterization of Microbial Communities in Ixodes persulcatus (Ixodida: Ixodidae), a Veterinary and Medical Important Tick Species in Northeastern China. J Med Entomol. 2020, 57(4):1270-1276. (IF:2.278) 

(15)  Qingniao Zhou; Chengbang Wang; Yuanyuan Zhu; Qunying Wu; Yonghua Jiang;Yuanjie Huang; Yanling Hu*; Key Genes And Pathways Controlled By E2F1 In Human Castration-Resistant Prostate Cancer Cells, OncoTargets and Therapy, 2019, 0: 8961-8976.（IF: 3.046） 

(16) Yanling Hu#; Aihua Tan#; Lei Yu#; Chenyang Hou#; Haofa Kuang#; Qunying Wu; Jinghan Su; Qingniao Zhou; Yuanyuan Zhu; Chenqi Zhang; Wei Wei; Lianfeng Li; Weidong Li; Yuanjie Huang; Hongli Huang; Xing Xie; Tingxi Lu; Haiying Zhang; Xiaobo Yang; Yong Gao; Tianyu Li; Yonghua Jiang*; Zengnan Mo*; A phenomics-based approach for the detection and interpretation of shared genetic influences on 29 biochemical indices in southern Chinese men. BMC genomics, BMC genomics, 2019, 20(1).（IF: 3.501） 

(17) Li W#, Zhou Q#, Gao Y, Jiang Y, Huang Y, Mo Z, Zou Y*, Hu Y*. eQTL analysis from co-localization of 2739 GWAS loci detects associated genes across 14 human cancers. J Theor Biol. 2019 Feb 7;462:240-246.（IF: 1.875） 

(18) Gao Y#, Wei L#, Wang C#, Huang Y, Li W, Li T, Mo C, Qin H, Zhong X, Wang Y, Tan A, Mo Z, Jiang Y*, Hu Y*. Chronic prostatitis alters the prostatic microenvironment and accelerates preneoplastic lesions in C57BL/6 mice. Biol Res. 2019 May 14;52(1):30.（IF: 2.482） 

(19) Chen QY#, Hu YL#, Wang XY, Harrison TJ, Wang C, Hu LP, Yang QL, Ren CC, Jia HH, Fang AZ*. Locus 5p13.1 may be associated with the selection of cancer-related HBV core promoter mutations. Int J Med Sci. 2019, 16(7):990-997. (IF:2.333) 

(20) Xin X#, Gu Y#, Chen Y, Huang Y, Mo Z*, Hu Y*. Functional analysis implicates the SNP rs61552325 in ERBB2 as an effector for androgen-insensitive prostate cancer cell invasion. Oncotarget. 2017 May 16;8(20):33745-33755.（IF: 5.168） 

(21) Gu Y, Zou YM, Lei D, Huang Y, Li W, Mo Z, Hu Y*. Promoter DNA methylation analysis reveals a novel diagnostic CpG-based biomarker and RAB25 hypermethylation in clear cell renal cell carcinoma. Sci Rep. 2017 Oct 27;7(1):14200.  （IF: 4.259） 

(22) Xuan Q#, Zhong X#, Li W, Mo Z, Huang Y*, Hu Y*. CtBP2 is associated with angiogenesis and regulates the apoptosis of prostate cancer cells. Oncol Rep. 2017 Aug;38(2):1259-1267.（IF: 2.662） 

(23) Tang Y#, Jiang S#, Gu Y, Li W, Mo Z, Huang Y, Li T, Hu Y*. Promoter DNA methylation analysis reveals a combined diagnosis of CpG-based biomarkers for prostate cancer. Oncotarget. 2017 Mar 22;8(35):58199-58209.（IF: 5.168） 

(24) Chen QY#, Hu YL#, Wang XY, Harrison TJ, Wang C, Hu LP, Yang QL, Ren CC, Jia HH, Fang AZ*. Locus 5p13.1 may be associated with the selection of cancer-related HBV core promoter mutations. Int J Med Sci. 2019 Jun 10;16(7):990-997.（IF: 2.333） 

(25) Li M, Tang Y, Lin C, Huang Q, Lei D*, Hu Y*. Serum Macroelement and Microelement Concentrations in Patients with Polycystic Ovary Syndrome: a Cross-Sectional Study. Biol Trace Elem Res. 2017 Mar;176(1):73-80.（IF: 2.399 ） 

(26) Li Y#, Si L#, Zhai Y#, Hu Y#, Hu Z#, Bei JX#, Xie B, Ren Q, Cao P, Yang F, Song Q, Bao Z, Zhang H, Han Y, Wang Z, Chen X, Xia X, Yan H, Wang R, Zhang Y, Gao C, Meng J, Tu X, Liang X, Cui Y, Liu Y, Wu X, Li Z, Wang H, Li Z, Hu B, He M, Gao Z, Xu X, Ji H, Yu C, Sun Y, Xing B, Yang X, Zhang H, Tan A, Wu C, Jia W, Li S, Zeng YX*, Shen H*, He F*, Mo Z*, Zhang H*, Zhou G*. Genome-wide association study identifies 8p21.3 associated with persistent hepatitis B virus infection among Chinese. Nat Commun. 2016, 7:11664.（IF: 11.329） 

 

Academic awards 

(1) Hu Yanling (1/9); Research on genetic information and applications for complex diseases using multi-center data integration and analysis, Guangxi Zhuang Autonomous Region People's Government, Science and Technology Progress, Second Prize of the Province and Ministry, 2018 (Hu Yanling; Chen Yang; Kong Kuo; Li Jianling; Li Liuming; Mo Zengnan; Zhou Qingniao; Huang Yuanjie; Li Tianyu). (Research Award) 

(2) Hu Yanling (2/6); Innovation and application of key technologies for early diagnosis, systematic treatment and prognosis assessment of prostate cancer in Chinese people, Guangdong People's Government, Technological Progress, Second Prize of the Province and Ministry, 2020 (Zhao Shanchao; Hu Yanling; Feng Ninghan; Chen Mingkun; Bao Jiming; Wang Chong). (Scientific Research Award) 
 

Professional Affiliations 

1. 2017-2022 Asia-Pacific Medical Biological Immunology Society Basic Immunology Branch Standing Committee 

2. 2017-2021 Asia-Pacific Medical Biological Immunology Society Director 

3. 2017 The First Council of the Primatology Branch of the Zoological Society of China Director 

4. 2019-2023 Invited editorial board member of the Chinese Journal of Cancer Prevention and Treatment 

5. 2019.8-present Standing committee member of the First Professional Committee of Emerging and Re-emerging Infectious Diseases of the Guangxi Preventive Medicine Association